Hmm. I'm not a huge Muse fan. I love their song Starlight, and heard it way back in late 2006/early 2007 (cannot remember when), and I know for a fact not many people in my neck of the woods heard it then.
I'd play it last year, and my friends who are self-confessed Muse fans would ask who sings it, I was just like....
I'm not so much a fan of their newer stuff, but maybe that's because it's so Twilight-related, and I'm not massive on Twilight?